Article
Variability in Human Bitter Taste Sensitivity to Chemically Diverse Compounds Can Be Accounted for by Differential TAS2R Activation.
Chemical senses - 1 Jul 2015
Roura Eugeni, Aldayyani Asya, Thavaraj Pridhuvi, Prakash Sangeeta, Greenway Delma, Thomas Walter G, Meyerhof Wolfgang, Roudnitzky Natacha, Foster Simon R
Abstract excerpt
The human population displays high variation in taste perception. Differences in individual taste sensitivity may also impact on nutrient intake and overall appetite. A well-characterized example is the variable perception of bitter compounds such as 6-n-propylthiouracil (PROP) and phenylthiocarbamide (PTC), which can be accounted for at the molecular level by polymorphic variants in the specific type 2 taste...
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