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Article

Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites.

Genes & development - 15 Apr 2013

Teplova Marianna, Hafner Markus, Teplov Dmitri, Essig Katharina, Tuschl Thomas, Patel Dinshaw J

Abstract excerpt

Mammalian Quaking (QKI) and its Caenorhabditis elegans homolog, GLD-1 (defective in germ line development), are evolutionarily conserved RNA-binding proteins, which post-transcriptionally regulate target genes essential for developmental processes and myelination. We present X-ray structures of the STAR (signal transduction and activation of RNA) domain, composed of Qua1, K homology (KH), and Qua2 motifs of QKI...

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Identifiers

PMID: 23630077
DOI: 10.1101/gad.216531.113
PMCID: PMC3650229

Genes

QKI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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