Article
The KH domain protein encoded by quaking functions as a dimer and is essential for notochord development in Xenopus embryos.
Genes & development - 1 Sept 1997
Zorn A M, Krieg P A
Abstract excerpt
Mutations in the mouse indicate that quaking gene function is essential for both embryogenesis and for development of the nervous system. Recent isolation of the mouse quaking gene identified a putative RNA-binding protein containing a single KH domain. We have previously isolated the Xenopus homolog of quaking, Xqua, and shown that the sequence is highly conserved through evolution. Here, we report experimental...
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