Article
Genetic polymorphisms of CYP2E1, GST, and NAT2 enzymes are not associated with risk of breast cancer in a sample of Lebanese women.
Mutation research - 1 Jan 2000
Zgheib Nathalie K, Shamseddine Ashraf A, Geryess Eddy, Tfayli Arafat, Bazarbachi Ali, Salem Ziad, Shamseddine Ali, Taher Ali, El-Saghir Nagi S
Abstract excerpt
Changes in the activity of drug metabolizing enzymes (DMEs) are potentially associated with cancer risk. This relationship is attributed to their involvement in the bioactivation of multiple procarcinogens or the metabolism of multiple substrates including an array of xenobiotics and environmental carcinogens. 326 Lebanese women of whom 99 were cancer free (controls) and 227 were diagnosed with breast cancer...
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