Article
Impact of agr dysfunction on virulence profiles and infections associated with a novel methicillin-resistant Staphylococcus aureus (MRSA) variant of the lineage ST1-SCCmec IV.
BMC microbiology - 27 Apr 2013
Ferreira Fabienne Antunes, Souza Raquel Rodrigues, de Sousa Moraes Bruno, de Amorim Ferreira Ana Maria, Américo Marco Antônio, Fracalanzza Sérgio Eduardo Longo, Dos Santos Silva Couceiro José Nelson, Sá Figueiredo Agnes Marie
Abstract excerpt
BACKGROUND: A novel variant of the ST1-SCCmecIV methicillin-resistant Staphylococcus aureus (MRSA) lineage, mostly associated with nosocomial bloodstream infections (BSI), has emerged in Rio de Janeiro. Bacterial biofilm has been considered a major virulence factor in central venous catheter-associated BSI. The mechanisms involved in biofilm formation/accumulation are multifactorial and complex. Studies have...
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