Article
Vancomycin MIC and agr dysfunction in invasive MRSA infections in southern Brazil.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] - 1 Dec 2020
Rossato Adriana Medianeira, Primon-Barros Muriel, Dias Cícero Armídio Gomes, d'Azevedo Pedro Alves
Abstract excerpt
In methicillin-resistant Staphylococcus aureus (MRSA) treatment, the vancomycin minimum inhibitory concentration (MIC) increase, vancomycin heteroresistance (hVISA) presence, and accessory gene regulator (agr) dysfunction are predictors of vancomycin therapy failure. This study evaluated the association between vancomycin MIC (≥ 1.0 μg/mL) and agr dysfunction in invasive MRSA isolates. Vancomycin MIC, hVISA...
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