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Article

Nasal carriage as a source of agr-defective Staphylococcus aureus bacteremia.

The Journal of infectious diseases - 1 Oct 2012

Smyth Davida S, Kafer Jared M, Wasserman Gregory A, Velickovic Lili, Mathema Barun, Holzman Robert S, Knipe Tiffany A, Becker Karsten, von Eiff Christof, Peters Georg, Chen Liang, Kreiswirth Barry N, Novick Richard P, Shopsin Bo

Abstract excerpt

Inactivating mutations in the Staphylococcus aureus virulence regulator agr are associated with worse outcomes in bacteremic patients. However, whether agr dysfunction is primarily a cause or a consequence of early bacteremia is unknown. Analysis of 158 paired S. aureus clones from blood and nasal carriage sites in individual patients revealed that recovery of an agr-defective mutant from blood was usually...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22859823
DOI: 10.1093/infdis/jis483
PMCID: PMC3448967

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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