Article
Lack of influence of TP53 Arg72Pro and 16bp duplication polymorphisms on risk of breast cancer in Iran.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Gohari-Lasaki Sahar, Gharesouran Jalal, Ghojazadeh Morteza, Montazeri Vahid, Mohaddes Ardebili Seiied Moitaba
Abstract excerpt
TP53 is assumed to be a very important tumour suppressor gene, as illustrated by recent reports that have shown effects of its polymorphisms on breast cancer risk. Arg72Pro and PIN3(16bp duplication) polymorphisms are proposed to have an effective role in structural changes of p53 and have therefore attracted interest as a risk factor for breast cancer in different populations. The aim of this study was to...
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