Article
Humoral immune responses to MUC1 in women with a BRCA1 or BRCA2 mutation.
European journal of cancer (Oxford, England : 1990) - 1 Jul 2007
Hermsen B B J, Verheijen R H M, Menko F H, Gille J J P, van Uffelen K, Blankenstein M A, Meijer S, van Diest P J, Kenemans P, von Mensdorff-Pouilly S
Abstract excerpt
INTRODUCTION: Breast cancer patients with early disease and a natural humoral response to MUC1 have a favourable prognosis, suggesting a possible role of MUC1 antibodies (ab) in controlling haematogenous tumour dissemination and outgrowth. The aim of the study was to evaluate humoral immune responses to MUC1 in women at hereditary high risk of breast cancer to investigate whether this immune response could play a...
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