Article
Whole genome identity-by-descent determination.
Journal of bioinformatics and computational biology - 1 Apr 2013
Sabaa Hadi, Cai Zhipeng, Wang Yining, Goebel Randy, Moore Stephen, Lin Guohui
Abstract excerpt
High-throughput single nucleotide polymorphism genotyping assays conveniently produce genotype data for genome-wide genetic linkage and association studies. For pedigree datasets, the unphased genotype data is used to infer the haplotypes for individuals, according to Mendelian inheritance rules. Linkage studies can then locate putative chromosomal regions based on the haplotype allele sharing among the pedigree...
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