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Article

Impact of two common xeroderma pigmentosum group D (XPD) gene polymorphisms on risk of prostate cancer.

PloS one - 1 Jan 2012

Mi Yuanyuan, Zhang Lifeng, Feng Ninghan, Wu Sheng, You Xiaoming, Shao Hongbao, Dai Feng, Peng Tao, Qin Feng, Zou Jiangang, Zhu Lijie

Abstract excerpt

BACKGROUND: DNA repair genes (EG: xeroderma pigmentosum group D, XPD) may affect the capacity of encoded DNA repair enzymes to effectively remove DNA adducts or lesions, which may result in enhanced cancer risk. The association between XPD gene polymorphisms and the susceptibility of prostate cancer (PCa) was inconsistent in previous studies. METHODOLOGY/PRINCIPAL FINDINGS: A meta-analysis based on 9 independent...

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Identifiers

PMID: 23028604
DOI: 10.1371/journal.pone.0044756
PMCID: PMC3448601

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