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Cancer Stem Cells: A Minor Cancer Subpopulation that Redefines Global Cancer Features

1 Jan 2013

Abstract excerpt

In recent years cancer stem cells (CSCs) have been hypothesized to comprise only a minor subpopulation in solid tumors that drives tumor initiation, progression, and metastasis; the so-called "cancer stem cell hypothesis." While a seemingly trivial statement about numbers, much is put at stake. If true, the conclusions of many studies of cancer cell populations could be challenged, as the bulk assay methods upon...

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PMID: 23596563
DOI: 10.3389/fonc.2013.00076

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