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Cancer Stem Cells: Cellular Plasticity, Niche, and its Clinical Relevance

1 Jan 2016

Abstract excerpt

Cancer handles an estimated 7.6 million deaths worldwide per annum. A recent theory focuses on the role Cancer Stem Cells (CSCs) in driving tumorigenesis and disease progression. This theory hypothesizes that a population of the tumor cell with similar functional and phenotypic characteristics as normal tissue stem cells are responsible for formation and advancement of many human cancers. The CSCs subpopulation...

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PMID: 27891292
DOI: 10.4172/2157-7633.1000363

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