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Article

The Stemness Phenotype Model

8 Aug 2012

Abstract excerpt

The identification of a fraction of cancer stem cells (CSCs) associated with resistance to chemotherapy in most solid tumors leads to the dogma that eliminating this fraction will cure cancer. Experimental data has challenged this simplistic and optimistic model. Opposite to the classical cancer stem cell model, we introduced the stemness phenotype model (SPM), which proposed that all glioma cells possess stem...

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PMID: 22928120
DOI: 10.5402/2012/392647

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