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Article

The glutathione reductase GSR-1 determines stress tolerance and longevity in Caenorhabditis elegans.

PloS one - 1 Jan 2013

Lüersen Kai, Stegehake Dirk, Daniel Jens, Drescher Mike, Ajonina Irene, Ajonina Caroline, Hertel Patrick, Woltersdorf Christian, Liebau Eva

Abstract excerpt

Glutathione (GSH) and GSH-dependent enzymes play a key role in cellular detoxification processes that enable organism to cope with various internal and environmental stressors. However, it is often not clear, which components of the complex GSH-metabolism are required for tolerance towards a certain stressor. To address this question, a small scale RNAi-screen was carried out in Caenorhabditis elegans where...

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Identifiers

PMID: 23593298
DOI: 10.1371/journal.pone.0060731
PMCID: PMC3620388

Genes

GSR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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