Article
Genetic susceptibility loci, pesticide exposure and prostate cancer risk.
PloS one - 1 Jan 2013
Koutros Stella, Berndt Sonja I, Hughes Barry Kathryn, Andreotti Gabriella, Hoppin Jane A, Sandler Dale P, Yeager Meredith, Burdett Laurie A, Yuenger Jeffrey, Alavanja Michael C R, Beane Freeman Laura E
Abstract excerpt
Uncovering SNP (single nucleotide polymorphisms)-environment interactions can generate new hypotheses about the function of poorly characterized genetic variants and environmental factors, like pesticides. We evaluated SNP-environment interactions between 30 confirmed prostate cancer susceptibility loci and 45 pesticides and prostate cancer risk in 776 cases and 1,444 controls in the Agricultural Health Study. We...
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