Article
Joint associations between established genetic susceptibility loci, pesticide exposures, and risk of prostate cancer.
Environmental research - 15 Nov 2023
Hurwitz Lauren M, Beane Freeman Laura E, Andreotti Gabriella, Hofmann Jonathan N, Parks Christine G, Sandler Dale P, Lubin Jay H, Liu Jia, Jones Kristine, Berndt Sonja I, Koutros Stella
Abstract excerpt
More than 200 genetic variants have been independently associated with prostate cancer risk. Studies among farmers have also observed increased prostate cancer risk associated with exposure to specific organophosphate (fonofos, terbufos, malathion, dimethoate) and organochlorine (aldrin, chlordane) insecticides. We examined the joint associations between these pesticides, established prostate cancer loci, and...
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