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Article

Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancer.

Pharmacogenetics and genomics - 1 Oct 2011

Koutros Stella, Andreotti Gabriella, Berndt Sonja I, Hughes Barry Kathryn, Lubin Jay H, Hoppin Jane A, Kamel Freya, Sandler Dale P, Burdette Laurie A, Yuenger Jeffrey, Yeager Meredith, Alavanja Michael C R, Freeman Laura E Beane

Abstract excerpt

BACKGROUND: To explore associations with prostate cancer and farming, it is important to investigate the relationship between pesticide use and single nucleotide polymorphisms (SNPs) in xenobiotic metabolic enzyme (XME) genes. OBJECTIVE: [corrected] We evaluated pesticide-SNP interactions between 45 pesticides and 1913 XME SNPs with respect to prostrate cancer among 776 cases and 1444 controls in the Agricultural...

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Share to Epoxide Hydrolases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21716162
DOI: 10.1097/FPC.0b013e3283493a57
PMCID: PMC3172373

Genes

EPHX1
GCLC
MPO
TXNRD2

Provenance

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