Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in base excision repair pathway genes, pesticide exposure, and prostate cancer risk.

Environmental health perspectives - 1 Dec 2011

Barry Kathryn Hughes, Koutros Stella, Berndt Sonja I, Andreotti Gabriella, Hoppin Jane A, Sandler Dale P, Burdette Laurie A, Yeager Meredith, Freeman Laura E Beane, Lubin Jay H, Ma Xiaomei, Zheng Tongzhang, Alavanja Michael C R

Abstract excerpt

BACKGROUND: Previous research indicates increased prostate cancer risk for pesticide applicators and pesticide manufacturing workers. Although underlying mechanisms are unknown, evidence suggests a role of oxidative DNA damage. OBJECTIVES: Because base excision repair (BER) is the predominant pathway involved in repairing oxidative damage, we evaluated interactions between 39 pesticides and 394 tag...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair
Share to Likelihood Functions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Logistic Models

Share to N-Glycosyl Hydrolases

Share to North Carolina

Share to Occupational Exposure

Share to Pesticides

Share to Prostatic Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 21810555
DOI: 10.1289/ehp.1103454
PMCID: PMC3261977

Genes

NEIL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in base excision repair pathway genes, pesticide exposure, and prostate cancer risk.PMID 21810555Read ↗

Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer risk.Semantic proximity Read ↗

Joint associations between established genetic susceptibility loci, pesticide exposures, and risk of prostate cancer.Semantic proximity Read ↗

Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancer.Semantic proximity Read ↗

Pesticide exposure and inherited variants in vitamin d pathway genes in relation to prostate cancer.Semantic proximity Read ↗

Genetic susceptibility loci, pesticide exposure and prostate cancer risk.Semantic proximity Read ↗

Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancer.Semantic proximity Read ↗

Genetic variants in xenobiotic detoxification enzymes, antioxidant defenses and hormonal pathways as biomarkers of susceptibility to prostate cancer.Semantic proximity Read ↗

Exploring the Utility of Expanded Clinical Exome Sequencing in Cancer Patients with Pesticide Exposure: Insights from Blood SamplesSemantic proximity Read ↗

Genetic profile for the detection of susceptibility to poisoning by exposure to pesticides.Semantic proximity Read ↗

Pesticides, gene polymorphisms, and bladder cancer among Egyptian agricultural workers.Semantic proximity Read ↗

Editor's Highlight: Base Excision Repair Variants and Pesticide Exposure Increase Parkinson's Disease Risk.Semantic proximity Read ↗

Role of PON1, SOD2, OGG1, XRCC1, and XRCC4 polymorphisms on modulation of DNA damage in workers occupationally exposed to pesticides.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.