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Article

Gene-environment interactions between JAZF1 and occupational and household lead exposure in prostate cancer among African American men.

Cancer causes & control : CCC - 1 Jul 2014

Neslund-Dudas Christine, Levin Albert M, Beebe-Dimmer Jennifer L, Bock Cathryn H, Nock Nora L, Rundle Andrew, Jankowski Michelle, Krajenta Richard, Dou Q Ping, Mitra Bharati, Tang Deliang, Rebbeck Timothy R, Rybicki Benjamin A

Abstract excerpt

PURPOSE: A single nucleotide polymorphism, rs10486567, in JAZF1 has consistently been associated with increased risk of prostate cancer. The physical interaction of zinc finger proteins, such as JAZF1, with heavy metals may play a role in carcinogenesis. This study assessed potential gene-environment statistical interactions (G×E) between rs10486567 and heavy metals in prostate cancer. METHODS: In a case-only...

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Source

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Identifiers

PMID: 24801046
DOI: 10.1007/s10552-014-0387-1
PMCID: PMC4267567

Genes

JAZF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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