Article
Mechanical, compositional, and structural properties of the mouse patellar tendon with changes in biglycan gene expression.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Sept 2013
Dourte Leann M, Pathmanathan Lydia, Mienaltowski Michael J, Jawad Abbas F, Birk David E, Soslowsky Louis J
Abstract excerpt
Tendons have complex mechanical properties that depend on their structure and composition. Some studies have assessed the role of small leucine-rich proteoglycans (SLRPs) in the mechanical response of tendon, but the relationships between sophisticated mechanics, assembly of collagen and SLRPs have not been well characterized. In this study, biglycan gene expression was varied in a dose dependent manner using...
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