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Investigating the temporal roles of decorin and biglycan in tendon healing

3 May 2023

Abstract excerpt

The small leucine-rich proteoglycans, decorin and biglycan, are minor components of the tendon extracellular matrix that regulate fibrillogenesis and matrix assembly. Our study objective was to define the temporal roles of decorin and biglycan during tendon healing using inducible knockout mice to include genetic knockdown at specific phases of healing: time of injury, the proliferative phase, and the remodeling...

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PMID: 37132501
DOI: 10.1002/jor.25590

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