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Article

Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification

14 Feb 2018

Abstract excerpt

Malformations of the sympathetic nervous system have been associated with cardiovascular instability, gastrointestinal dysfunction, and neuroblastoma. A better understanding of the factors regulating sympathetic nervous system development is critical to the development of potential therapies. Here, we have uncovered a temporal requirement for the LIM homeodomain transcription factor ISL1 during sympathetic...

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PMID: 29445148
DOI: 10.1038/s41419-018-0283-9

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