Article
Modulation of PF10_0355 (MSPDBL2) alters Plasmodium falciparum response to antimalarial drugs.
Antimicrobial agents and chemotherapy - 1 Jul 2013
Van Tyne Daria, Uboldi Alessandro D, Healer Julie, Cowman Alan F, Wirth Dyann F
Abstract excerpt
Malaria's ability to rapidly adapt to new drugs has allowed it to remain one of the most devastating infectious diseases of humans. Understanding and tracking the genetic basis of these adaptations are critical to the success of treatment and intervention strategies. The novel antimalarial resistance locus PF10_0355 (Pfmspdbl2) was previously associated with the parasite response to halofantrine, and functional...
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