Article
A new approach to HLA typing designed for solid organ transplantation: epityping and its application to the HLA-A locus.
International journal of immunogenetics - 1 Dec 2013
Lougee E, Morjaria S, Shaw O, Collins R, Vaughan R
Abstract excerpt
HLA-specific antibodies bind discrete clusters of amino acids called epitopes, but serological assignment of antibody specificities makes no reference to this. As HLA typing for solid organ transplantation is provided at only medium (serologically equivalent) resolution, this means that recipient HLA antibodies to donor HLA epitopes may not be identified. We have designed a novel and rapid HLA-A epitope typing...
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