Article
MicroRNA 125 represses nonsense-mediated mRNA decay by regulating SMG1 expression.
Biochemical and biophysical research communications - 24 May 2013
Wang Gang, Jiang Bowen, Jia Chenliang, Chai Baofeng, Liang Aihua
Abstract excerpt
Nonsense-mediated mRNA decay (NMD) is a cellular response mechanism that eliminates aberrant mRNA transcripts and thereby prevents the production of potentially deleterious C-terminally truncated proteins. The phosphatidylinositol 3-kinase-related protein kinase SMG1 is considered to be an essent...
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