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Article

MicroRNA‑125b regulates Alzheimer's disease through SphK1 regulation

13 Jun 2018

Abstract excerpt

The present study aimed to investigate the expression of microRNA (miR)‑125b in patients with Alzheimer's disease (AD) and to determine its potential role in AD. Mouse neuroblastoma Neuro2a APPSwe/Δ9 cells were used to generate an in vitro AD model. The results demonstrated that the expression levels of miR‑125b were markedly increased in patients with AD compared with in the normal group. In addition,...

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PMID: 29901156
DOI: 10.3892/mmr.2018.9156

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