Article
Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA.
Human molecular genetics - 1 May 2007
Duan Ranhui, Pak Changhui, Jin Peng
Abstract excerpt
MicroRNAs (miRNAs) are small non-coding RNAs that inhibit expression of specific target genes at the post-transcriptional level. Sequence variations in miRNA genes, including pri-miRNAs, pre-miRNAs and mature miRNAs, could potentially influence the processing and/or target selection of miRNAs. In this study, we have systematically identified single nucleotide polymorphisms (SNPs) associated with 227 known human...
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