Article
Unraveling a complex genetic disease: age-related macular degeneration.
Survey of ophthalmology - 1 Jan 2000
Chamberlain Matt, Baird Paul, Dirani Mohamed, Guymer Robyn
Abstract excerpt
In most of the Western world, age-related macular degeneration (AMD) remains the largest single cause of severe visual impairment, and its prevalence continues to increase. It is considered to be a complex disease, in which multiple genes and environment play a role in pathogenesis. Several environmental insults are implicated with smoking, serum cholesterol, hypertension, sunlight exposure, and many other...
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