Article
Phenotype of capillaries in skeletal muscle of nNOS-knockout mice.
American journal of physiology. Regulatory, integrative and comparative physiology - 15 Jun 2013
Baum Oliver, Vieregge Max, Koch Pascale, Gül Safak, Hahn Sabine, Huber-Abel Felicitas A M, Pries Axel R, Hoppeler Hans
Abstract excerpt
Because neuronal nitric oxide synthase (nNOS) has a well-known impact on arteriolar blood flow in skeletal muscle, we compared the ultrastructure and the hemodynamics of/in the ensuing capillaries in the extensor digitorum longus (EDL) muscle of male nNOS-knockout (KO) mice and wild-type (WT) littermates. The capillary-to-fiber (C/F) ratio (-9.1%) was lower (P ≤ 0.05) in the nNOS-KO mice than in the WT mice,...
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