Article

Becker muscular dystrophy mice showed site-specific decay of type IIa fibers with capillary change in skeletal muscle

2024-10-18

Abstract excerpt

Becker muscular dystrophy (BMD), an X-linked muscular dystrophy, is mostly caused by an in-frame deletion of DMD . BMD severity varies from asymptomatic to severe, associated with the genotype of DMD . However, the underlying mechanisms remain unclear. We established BMD mice carrying three representative exon deletions: ex45–48 del., ex45–47 del., and ex45–49 del. (d45–48, d45–47 and d45–49), with high frequen...

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Literature Corpus work: 32e3de99-8bb0-5138-a873-d2bcb7a991bb
DOI: 10.1101/2024.10.15.618443

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