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Article

HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis.

Autophagy - 2 Jan 2017

Watanabe Yoshihisa, Tsujimura Atsushi, Taguchi Katsutoshi, Tanaka Masaki

Abstract excerpt

Proteostasis is important for protecting cells from harmful proteins and is mainly controlled by the HSF1 (heat shock transcription factor 1) stress response pathway. This pathway facilitates protein refolding by molecular chaperones; however, it is unclear whether it functions in autophagy or inclusion formation. The autophagy receptor SQSTM1/p62 is involved in selective autophagic clearance and inclusion...

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Source

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Identifiers

PMID: 27846364
DOI: 10.1080/15548627.2016.1248018
PMCID: PMC5240838

Genes

SQSTM1
HSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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