Article
HLA typing in Brazilian boys with aromatic antiepileptic drug-induced DRESS.
International journal of clinical pharmacy - 1 Jun 2013
Gaeti Walderez Penteado, Obreli-Neto Paulo Roque, Moliterno Ricardo A, Schiavon Gina Bressan, Cuman Roberto Kenji Nakamura
Abstract excerpt
CASES DESCRIPTION: We report two cases of drug rash with eosinophilia and systemic symptoms (DRESS) associated with the use of carbamazepine and phenytoin in Brazilian boys tested for human leukocyte antigen (HLA) class I and II alleles. The clinical manifestations were similar: a maculopapular eruption progressing to exfoliative erythroderma, fever, and lymphadenopathy. Leukocytosis, atypical lymphocytes, and...
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