Article
[Tumor suppressor role of chromatin-remodeling factor ARID1A].
Yi chuan = Hereditas - 1 Mar 2013
Guo Xiao-Qiang, Zhang Qiao-Xia, Huang Wei-Ren, Duan Xiang-Lin, Cai Zhi-Ming
Abstract excerpt
The mammalian SWI/SNF complex is one of ATP-dependent chromatin-remodeling complexes, which plays important roles in cell proliferation, differentiation, development and tumor suppression. ARID1A (AT-rich interactive domain-containing protein 1A) is a large subunit of SWI/SNF complex, and also an ARID family member with non- sequence-specific DNA binding activity. ARID1A is a tumor suppressor gene which is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
