Article

Diagnostic significance and prognostic role of the ARID1A gene in cancer outcomes (Review)

2020-01-31

Abstract excerpt

Mutations of the ARID1A gene, which encodes the basic directional subunit of SWI/SNF chromatin remodeling complexes, were detected in the middle of the last decade in several cancerous tissue types, highlighting its tumour‑suppressive role. Since then, functional studies of the homologous protein have indicated that through its interactions with nucleosomal DNA, transcription factors and nuclear hormone receptors,...

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Literature Corpus work: 5d5d1ff4-6698-53e9-8166-674b481c7462
DOI: 10.3892/wasj.2020.37

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