Article
Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density at forearm.
Journal of medical genetics - 1 Jul 2013
Zheng Hou-Feng, Duncan Emma L, Yerges-Armstrong Laura M, Eriksson Joel, Bergström Ulrica, Leo Paul J, Leslie William D, Goltzman David, Blangero John, Hanley David A, Carless Melanie A, Streeten Elizabeth A, Lorentzon Mattias, Brown Matthew A, Spector Tim D, Pettersson-Kymmer Ulrika, Ohlsson Claes, Mitchell Braxton D, Richards J Brent
Abstract excerpt
BACKGROUND: Forearm fractures affect 1.7 million individuals worldwide each year and most occur earlier in life than hip fractures. While the heritability of forearm bone mineral density (BMD) and fracture is high, their genetic determinants are largely unknown. AIM: To identify genetic variants associated with forearm BMD and forearm fractures. METHODS: BMD at distal radius, measured by dual-energy x-ray...
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