Article
The genetics of innate immunity sensors and human disease.
International reviews of immunology - 1 Apr 2013
Pothlichet Julien, Quintana-Murci Lluis
Abstract excerpt
Since their discovery, innate immunity microbial sensors have been increasingly studied and shown to play a critical role in innate responses to microbes in several experimental in vitro, ex vivo, and animal models. However, their role in the human response to infection in natural conditions has just started to be deciphered, by means of clinical studies of primary immunodeficiencies and epidemiological genetic...
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