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Article

Primary Immunodeficiencies and Inflammatory Disease: A Growing Genetic Intersection.

Trends in immunology - 1 Feb 2016

Fodil Nassima, Langlais David, Gros Philippe

Abstract excerpt

Recent advances in genome analysis have provided important insights into the genetic architecture of infectious and inflammatory diseases. The combined analysis of loci detected by genome-wide association studies (GWAS) in 22 inflammatory diseases has revealed a shared genetic core and associated biochemical pathways that play a central role in pathological inflammation. Parallel whole-exome sequencing studies...

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Identifiers

PMID: 26791050
DOI: 10.1016/j.it.2015.12.006
PMCID: PMC4738049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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