Article
CC chemokine receptor-3 as new target for age-related macular degeneration.
Gene - 1 Jul 2013
Sharma Neel Kamal, Gupta Amod, Prabhakar Sudesh, Singh Ramandeep, Bhatt Arvind Kumar, Anand Akshay
Abstract excerpt
CC chemokine receptor-3 (CCR3) is involved in angiogenic processes. Recently, CCR3 was accounted to participate in choroidal neovascularization (CNV) and CCR3 targeting was reported to be superior to standard antivascular endothelial growth factor-A (VEGF-A) administration when tested in an artificially induced CNV in animals. As human CCR3 studies are lacking in age-related macular degeneration (AMD) patients we...
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