Article
Association of c3 gene polymorphisms with neovascular age-related macular degeneration in a chinese population.
Current eye research - 1 Aug 2009
Pei Xue-Ting, Li Xiao-Xin, Bao Yong-Zhen, Yu Wen-Zhen, Yan Zheng, Qi Hui-Jun, Qian Tong, Xiao Hong-Xiang
Abstract excerpt
PURPOSE: The purpose of this study was to determine whether the genetic polymorphisms of complement factor 3 (C3) are associated with neovascular age-related macular degeneration (AMD) in the Chinese population. METHODS: A total of 123 unrelated Chinese Han patients with neovascular AMD and 130 control subjects were recruited. Their six single-nucleotide polymorphisms (SNPs) in the C3 gene, one in the complement...
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