Article
Association of toll-like receptor 3 polymorphism rs3775291 with age-related macular degeneration: a systematic review and meta-analysis.
Scientific reports - 22 Jan 2016
Ma Li, Tang Fang Yao, Chu Wai Kit, Young Alvin L, Brelen Marten E, Pang Chi Pui, Chen Li Jia
Abstract excerpt
Association of a polymorphism rs3775291 in the toll-like receptor 3 (TLR3) gene with age-related macular degeneration (AMD) had been investigated intensively, with variable results across studies. Here we conducted a meta-analysis to verify the effect of rs3775291 on AMD. We searched for genetic association studies published in PubMed, EMBASE and Web of Science from start dates to March 10, 2015. Totally 235...
Topics
- Choroidal Neovascularization
- Genes, Recessive
- Genetic Association Studies
- Genetic Predisposition to Disease
- Homozygote
- Humans
- Macular Degeneration
- Models, Genetic