Mutation induction in Chinese hamster lung V79 cells by five alk-2-enals produced by lipid peroxidation.

doi:10.1016/0165-7992(90)90065-r

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Article

Mutation induction in Chinese hamster lung V79 cells by five alk-2-enals produced by lipid peroxidation.

Mutation research - 1 Jun 1990

Canonero R, Martelli A, Marinari U M, Brambilla G

Abstract excerpt

Five alk-2-enals--pent-2-enal, hex-2-enal, hept-2-enal, oct-2-enal and non-2-enal--produced by lipid peroxidation were tested for mutagenic activity in V79 Chinese hamster cells. At concentrations ranging from 0.003 to 0.3 mM all 5 alk-2-enals induced a dose-dependent increase in the frequency of...

Topics

Aldehydes
Animals
Cell Line
Lipid Peroxidation
Mutagenicity Tests
Mutation

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