Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts

Abstract excerpt

A number of promutagenic exocyclic DNA adducts have recently been detected in both humans and rodents without carcinogen treatment. These observations raised questions about their origins and potential significance in carcinogenesis. In this commentary, we present our views pertaining to the in vivo sources of these cyclic adducts, specifically the cyclic propano and etheno adducts. The basis for our discussion...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antioxidant Activity and Oxidative Stress
• Share to Carcinogens and Genotoxicity Assessment
• Share to Genomics, phytochemicals, and oxidative stress