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Article

Ochratoxin A-induced mutagenesis in mammalian cells is consistent with the production of oxidative stress.

Chemical research in toxicology - 1 Jul 2007

Palma Nieves, Cinelli Serena, Sapora Orazio, Wilson Samuel H, Dogliotti Eugenia

Abstract excerpt

Ochratoxin A (OTA) is a widespread mycotoxin in food and a powerful nephrocarcinogen in rats. The mutagenicity of OTA has been extensively investigated but with conflicting results, thus leaving open the mechanistic question for OTA carcinogenicity. Here, we examined the mutagenicity of OTA by using well-standardized mutation assays such as the hypoxanthine-guanine phosphoribosyltransferase (HPRT) assay in...

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Identifiers

PMID: 17567156
DOI: 10.1021/tx700027j
PMCID: PMC2367102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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