Article
Pre-S deletion and complex mutations of hepatitis B virus related to young age hepatocellular carcinoma in Qidong, China.
PloS one - 1 Jan 2013
Qu Lishuai, Kuai Xiaoling, Liu Taotao, Chen Taoyang, Ni Zhengpin, Shen Xizhong
Abstract excerpt
BACKGROUND/AIM: To investigate the roles of biomedical factors, hepatitis B virus (HBV) DNA levels, genotypes, and specific viral mutation patterns on the progression of hepatocellular carcinoma (HCC) patients below 40 years of age in Qidong, China. METHODS: We conducted a case-control study within a cohort of 2387 male HBV carriers who were recruited from August, 1996. The HBV DNA sequence was determined in 49...
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