Article
Pre-S deletion and complex mutations of hepatitis B virus related to advanced liver disease in HBeAg-negative patients.
Gastroenterology - 1 Nov 2007
Chen Chien-Hung, Hung Chao-Hung, Lee Chuan-Mo, Hu Tsung-Hui, Wang Jing-Houng, Wang Jyh-Chwan, Lu Sheng-Nan, Changchien Chi-Sin
Abstract excerpt
BACKGROUND & AIMS: This longitudinal study investigated the interactions and roles of hepatitis B virus (HBV) genotypes, pre-S deletions, and core promoter and precore mutations on the progression of liver disease in hepatitis B e antigen (HBeAg)-negative patients. METHODS: A total of 141 HBeAg-negative patients without liver cirrhosis or hepatocellular carcinoma at study entry were recruited for this study,...
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