Article
Eyes absent tyrosine phosphatase activity is not required for Drosophila development or survival.
PloS one - 1 Jan 2013
Jin Meng, Jusiak Barbara, Bai Zengliang, Mardon Graeme
Abstract excerpt
Eyes absent (Eya) is an evolutionarily conserved transcriptional coactivator and protein phosphatase that regulates multiple developmental processes throughout the metazoans. Drosophila eya is necessary for survival as well as for the formation of the adult eye. Eya contains a tyrosine phosphatase domain, and mutations altering presumptive active-site residues lead to strongly reduced activities in ectopic eye...
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