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Article

MAPK target sites of eyes absent are not required for eye development or survival in Drosophila.

PloS one - 1 Jan 2012

Jusiak Barbara, Abulimiti Abuduaini, Haelterman Nele, Chen Rui, Mardon Graeme

Abstract excerpt

Eyes absent (Eya) is a highly conserved transcription cofactor and protein phosphatase that plays an essential role in eye development and survival in Drosophila. Ectopic eye induction assays using cDNA transgenes have suggested that mitogen activated protein kinase (MAPK) activates Eya by phosphorylating it on two consensus target sites, S402 and S407, and that this activation potentiates the ability of Eya to...

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Identifiers

PMID: 23251383
DOI: 10.1371/journal.pone.0050776
PMCID: PMC3520925

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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