Article
Xeya3 regulates survival and proliferation of neural progenitor cells within the anterior neural plate of Xenopus embryos.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 2007
Kriebel Martin, Müller Frank, Hollemann Thomas
Abstract excerpt
The transcriptional coactivater and tyrosine phosphatase eyes absent (eya) is vital for eye development in Drosophila. We identified a vertebrate member of the Eya family, Xeya3, which is expressed in the anterior neural plate, including the eye field. Overexpression of wild-type Xeya3 or of a phosphatase-negative version of Xeya3 creates massive enlargements of brain and retinal tissues, mainly caused by...
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