Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variations in the serotoninergic system contribute to body-mass index in Chinese adolescents.

PloS one - 1 Jan 2013

Chen Chunhui, Chen Wen, Chen Chuansheng, Moyzis Robert, He Qinghua, Lei Xuemei, Li Jin, Wang Yunxin, Liu Bin, Xiu Daiming, Zhu Bi, Dong Qi

Abstract excerpt

OBJECTIVE: Obesity has become a worldwide health problem in the past decades. Human and animal studies have implicated serotonin in appetite regulation, and behavior genetic studies have shown that body mass index (BMI) has a strong genetic component. However, the roles of genes related to the serotoninergic (5-hydroxytryptamine,5-HT) system in obesity/BMI are not well understood, especially in Chinese subjects....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Mass Index

Share to Receptors, Serotonin

Share to Serotonin

Share to Vesicular Monoamine Transport Proteins

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 23554917
DOI: 10.1371/journal.pone.0058717
PMCID: PMC3598805

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variations in the serotoninergic system contribute to body-mass index in Chinese adolescents.PMID 23554917Read ↗

Contribution of the functional 5-HTTLPR variant of the SLC6A4 gene to obesity risk in male adults.Semantic proximity Read ↗

Association Between Body Mass Index and Depression/Anxiety in an East Asian Population: A Mendelian Randomization Study.Semantic proximity Read ↗

"Diminished" association between the serotonin transporter linked polymorphism (5HTTLPR) and body mass index in a large psychiatric sample.Semantic proximity Read ↗

Genetic polymorphism c.1438A>G of the 5-HT(2A) receptor is associated with abdominal obesity in Chinese Northern Han population.Semantic proximity Read ↗

A Systems Biology Approach to Investigating the Interaction between Serotonin Synthesis by Tryptophan Hydroxylase and the Metabolic HomeostasisSemantic proximity Read ↗

Serotonin transporter gene-linked polymorphic region: allele distributions in relationship to body weight and in anorexia nervosa.Semantic proximity Read ↗

Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels.Semantic proximity Read ↗

Interactions between genotype and depressive symptoms on obesity.Semantic proximity Read ↗

Further exploration of the possible influence of polymorphisms in HTR2C and 5HTT on body weight.Semantic proximity Read ↗

A controlled pharmacogenetic trial of sibutramine on weight loss and body composition in obese or overweight adults.Semantic proximity Read ↗

Serotonin receptor 2A -1438G/A promoter polymorphism in relation to obesity and response to sibutramine.Semantic proximity Read ↗

Association of polymorphisms in 5-HTT (SLC6A4) and MAOA genes with measures of obesity in young adults of Portuguese origin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.